The Wallace Lab

Image credit: Tom Humberstone


We study how organisms respond to their environment, focusing on molecular mechanisms used by fungi. We collect and analyze genome-scale datasets to understand how fungi dynamically reorganize their RNA and protein to adapt to environmental change. This includes how fungi adapt to infect human hosts.

Disambiguation: This is the Edward Wallace Lab studying RNA and Systems Biology in Fungi. It is not to be confused with the Stephen Wallace Lab studying Chemical and Synthetic Biology, also in Edinburgh.

News
Farewell Jing Qi, Welcome Eleanor and Marcos

Farewell Jing Qi Chong, who is moving on after doing a very nice Honours project analysing data on RNA-binding proteins.

Welcome to Eleanor Donohoe and Marcos Bermejo, who are both working on MSc Bioinformatics projects related to riboviz ribosome profiling data analysis.

Posted 26 May 2022 by Edward
Welcome Domenico

Welcome to Domenico, who is joining us to work on a PhD project joint with Ken Sawin, looking at post-transcriptional control in filamentous fungi.

Posted 04 Apr 2022 by Edward
Review paper on control of cell walls

A new review paper on RNA-binding proteins and the fungal cell wall is now available at The Cell Surface.

The review was a lovely collaboration with Rebecca Hall at Kent.

Posted 12 Jan 2022 by Edward
Farewell Flic

Flic is leaving the lab after 2.5 years! Flic has worked on riboviz bioinformatics, directly supervised several student projects, taught data skills as a Carpentries instructor, including with Ed-DaSH.

Flic’s next step is a PhD studying research software practice at epcc. We will miss her, but she will not be far away.

Posted 17 Dec 2021 by Edward
Posts
How to ask for data from a paper
Posted 13 Apr 2022 by Edward
How we combine open science and student research projects
Posted 13 Dec 2021 by Edward
Favourite Papers In The Lab
Posted 26 Nov 2020 by Flic
Safe and Productive Science-ing During an Epidemic
Posted 11 Mar 2020 by Edward
Papers
Limitations of composability of cis-regulatory elements in messenger RNA
Auxillos, Haynes, et al. bioRxiv 2022
Published 16 Apr 2022
riboviz 2: A flexible and robust ribosome profiling data analysis and visualization workflow
Cope et al. Bioinformatics 2022
Published 22 Feb 2022
Post-transcriptional control of fungal cell wall synthesis
Fungal Cell Walls, The Cell Surface 2022
Published 12 Jan 2022
The benefits of an open-science approach in student research projects
Open Student Projects, The Biochemist 2021
Published 13 Dec 2021